Iran's top nuclear negotiator Saeed Jalili has arrived in Geneva, where he is due to hold nuclear talks with William Burns, a senior American diplomat and EU Foreign Policy Chief Javier Solana on Saturday.

Saeed Jalili said Iran cares more about the approach the other side takes.

''What matters more than who is going to participate is the kind of approach they take. If they enter negotiations with a constructive approach and avoid the past mistakes, we could definitely have good and constructive talks."

In Washington, US Secretary of State Condoleezza said what happens on Saturday will be crucial to the future policy on Iran.

"We have been very clear that any country can change course.The United States doesn't have any permanent enemies and we hope that the signal that we're sending, that we fully support the track that Iran could take for a better relationship with the international community is one that the United States stands fully behind."

Meanwhile, Iranian Foreign Minister Manouchehr Mottaki said the forthcoming nuclear talks with the participation of a U.S. diplomat for the first time is a good signal for development ahead.

Mottaki said there might be an agreement both on the issue of opening a U.S. interest-protection bureau in Iran and on the issue of direct flights to Iran.

The U.S. Undersecretary of State for Political Affairs William Burns will attend the talks, joining colleagues from other world powers to meet with Iran's chief nuclear negotiator.